Challenges for the pharmaceutical technical development of protein coformulations

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Challenges for the pharmaceutical technical development of protein coformulations.

OBJECTIVES This review discusses challenges to stability, analytics and manufacturing of protein coformulations. Furthermore, general considerations to be taken into account for the pharmaceutical development of coformulated protein drug products are highlighted. KEY FINDINGS Coformulation of two or more active substances in one single dosage form has recently seen increasing use offering sev...

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ژورنال

عنوان ژورنال: Journal of Pharmacy and Pharmacology

سال: 2017

ISSN: 2042-7158,0022-3573

DOI: 10.1111/jphp.12731